Date of Award

Spring 2-2016

Embargo Period

8-2-2017

Degree Type

Dissertation

Degree Name

Doctor of Philosophy (PhD)

Department

Physics

Advisor(s)

Mathias Losche

Abstract

In this thesis we focus on the mechanistic understanding of two membrane mediated biological processes: retroviral assembly and endolysin PlyC plasma membrane translocation. Retroviral Gag polyprotein is the structural determinant that assembles in a protein lattice on the hosts plasma membrane to trigger formation of the viral protein/membrane shell.

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