Revealing the Structural and Molecular Basis of Retroviral Assemb.pdf (10.25 MB)
Revealing the Structural and Molecular Basis of Retroviral Assembly and Endolysin PlyC Membrane Translocation Using Surface Plasmon Resonance and Neutron Reflectometry
thesis
posted on 2016-02-01, 00:00 authored by Marilia Cabral do Rego BarrosIn this thesis we focus on the mechanistic understanding of two membrane mediated biological processes: retroviral assembly and endolysin PlyC plasma membrane translocation. Retroviral Gag polyprotein is the structural determinant that assembles in a protein lattice on the hosts plasma membrane to trigger formation of the viral protein/membrane shell.
History
Date
2016-02-01Degree Type
- Dissertation
Department
- Physics
Degree Name
- Doctor of Philosophy (PhD)