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Revealing the Structural and Molecular Basis of Retroviral Assemb.pdf (10.25 MB)

Revealing the Structural and Molecular Basis of Retroviral Assembly and Endolysin PlyC Membrane Translocation Using Surface Plasmon Resonance and Neutron Reflectometry

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thesis
posted on 2016-02-01, 00:00 authored by Marilia Cabral do Rego Barros

In this thesis we focus on the mechanistic understanding of two membrane mediated biological processes: retroviral assembly and endolysin PlyC plasma membrane translocation. Retroviral Gag polyprotein is the structural determinant that assembles in a protein lattice on the hosts plasma membrane to trigger formation of the viral protein/membrane shell.

History

Date

2016-02-01

Degree Type

  • Dissertation

Department

  • Physics

Degree Name

  • Doctor of Philosophy (PhD)

Advisor(s)

Mathias Losche

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