Date of Original Version

7-1-2012

Type

Article

PubMed ID

22743775

Rights Management

Copyright 2012 Nature America, Inc

Abstract or Description

Few technologies are more widespread in modern biological laboratories than imaging. Recent advances in optical technologies and instrumentation are providing hitherto unimagined capabilities. Almost all these advances have required the development of software to enable the acquisition, management, analysis and visualization of the imaging data. We review each computational step that biologists encounter when dealing with digital images, the inherent challenges and the overall status of available software for bioimage informatics, focusing on open-source options.

DOI

10.1038/nmeth.2084

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Published In

Nature methods, 9, 7, 697-710.