Title

The EB1 homolog Mal3 stimulates the ATPase of the kinesin Tea2 by recruiting it to the microtubule.

Date of Original Version

4-1-2005

Type

Article

PubMed ID

15665379

Abstract or Description

Tea2 is a kinesin family member from Schizosaccharomyces pombe that is targeted to microtubule tips and cell ends in a process that depends on Mal3. Constructs of Tea2 containing the motor domain only or the motor domain plus the N-terminal extension are monomeric, whereas a construct including the first predicted coiled coil region is dimeric. These constructs have a low basal rate of ATP hydrolysis of

DOI

10.1074/jbc.M413620200

 

Published In

The Journal of biological chemistry, 280, 13, 12299-12304.