Title

Striatal interneurons: causes of or cures for movement disorders?

Date of Original Version

10-5-2012

Type

Article

PubMed ID

23042880

Abstract or Description

Imagine one day you notice a tremor and can't walk easily anymore. Your doctor tells you that you have Parkinson's disease and gives you levodopa, a 60-year-old treatment that temporarily relieves your symptoms. But over time, the medication makes you impulsive, and after a few years, your symptoms return. The doctor tells you that you have developed resistance to your medicine and that nothing else is likely to work—your condition continues to degenerate. Sadly, this is the reality for millions of Americans suffering from Parkinson's disease.

DOI

10.1126/science.1229852

 

Published In

Science, 338, 6103, 59-59.