Title

Candida albicans adds more weight to iron regulation.

Date of Original Version

8-18-2011

Type

Article

PubMed ID

21843865

Abstract or Description

The pathogen Candida albicans can occupy both the bloodstream and gastrointesintal (GI) tract, niches that differ in iron availability. Chen et al. report that a distinct transcription factor, Sef1, alters the conserved fungal iron regulatory paradigm. Sef1 is pivotal for bloodstream infection, but contributes to GI tract colonization as well.

DOI

10.1016/j.chom.2011.08.001

 

Published In

Cell Host & Microbe, 10, 2, 93-94.