Title

Genetic control of Candida albicans biofilm development.

Date of Original Version

2-1-2011

Type

Article

PubMed ID

21189476

Abstract or Description

Candida species cause frequent infections owing to their ability to form biofilms - surface-associated microbial communities - primarily on implanted medical devices. Increasingly, mechanistic studies have identified the gene products that participate directly in the development of Candida albicans biofilms, as well as the regulatory circuitry and networks that control their expression and activity. These studies have uncovered new mechanisms and signals that govern C. albicans biofilm development and associated drug resistance, thus providing biological insight and therapeutic foresight.

DOI

10.1038/nrmicro2475

 

Published In

Nature reviews. Microbiology, 9, 2, 109-118.